Lung panel

Differential diagnosis		Most commonly used biomarkers
Lung carcinoma		TTF1	Napsin A	CK7	CK20	CK5/6	p40
		DUO p40/ Napsin A	DUO CK5/6/TTF1	Calretinin	Podoplanin	WT1	BAP1
		MTAP
	Adenocarcinoma vs Squamous cell carcinoma	TTF1	Napsin A	p40	CK5/6	DUO p40/ Napsin A	DUO CK5/6/TTF1
	Prognostic/ Predictive	PD-L1	ALK	ROS1
	Adenocarcinoma vs Mesothelioma	Calretinin	CK5/6	WT1	Podoplanin	BAP1	MTAP
		EpCAM	CEA	CD15	TTF1
Neuroendocrine neoplasms (incl. SCLC)		Synaptophysin	Chromogranin A	CD56	TTF1	Ki67	INSM1
Salivary gland type neoplasms		Pan CK	p40	EMA	S100	SOX10	ASMA
		Calponin	Myosin	CD117
Hematolymphoid neoplasms		CD45	CD3	CD20	CD10	BCL6	EBER
		PAX5	BCL2	CD1a	CD207
Mesenchymal neoplasms		S100	SOX10	Melan A	Melanosome	ERG	CD31
		CD34	Podoplanin	ASMA	Desmin	Caldesmon
	The bolded are the most used biomarkers