| Differential diagnosis |
Most commonly used biomarkers |
Melanoma (including biomarkers for sentinel lymph node)
|
SOX10 |
Melan A |
Melanosome (HMB45) |
Tyrosinase |
S100 |
BAP1 |
| CD63 |
Pan CK/ S100 |
Melanoma-Pan |
Melan A/ Ki67 |
BRAFv600E |
PRAME |
Paget disease
|
CK7 |
CK20 |
CDX2 |
ER |
MUC1 |
GCDFP-15 |
| HER2 |
|
|
|
|
|
Sebaceous tumour
|
EMA |
EpCAM |
GCDFP-15 |
MLH1 |
MSH2 |
MSH6 |
| PMS2 |
AR |
p53 |
Ki67 |
|
|
| Eccrine gland tumour |
Tumours luminal (CK7, CEA, EMA) |
Myoepithelial (CK5/6, CK14, S100, SOX10) |
p40 |
beta-Catenin |
| BCC/ SCC |
EpCAM |
CK5/6 |
CK14 |
p40 |
Pan-CK |
|
| Autoimmune and Immune-Mediated Diseases (AIM) |
FITC-C3 |
FITC-fibrinogen |
FITC-IgG |
FITC-IgA |
FITF-IgM |
|
| Infectious |
HSV-1 |
HSV-2 |
CMV |
Treponema pallidium |
VZV |
|
Other
|
CD34 |
Factor XIIIa |
CD3 |
CD31 |
CD68 |
Ki67 |
| ASMA |
Desmin |
CD117 |
Podoplanin |
CD43 |
CD63 (NKI/C3) |
| CD163 |
CD20 |
CD4 |
CD8 |
|
|
| The list above does not include all differential diagnosis and related biomarkers. The bolded are the most commonly used biomarkers |
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