| Differential diagnosis | Most commonly used biomarkers | |||||
|
Melanoma (including biomarkers for sentinel lymph node) |
SOX10 | Melan A | Melanosome (HMB45) | Tyrosinase | S100 | BAP1 |
| CD63 | Pan CK/ S100 | Melanoma-Pan | Melan A/ Ki67 | BRAFv600E | PRAME | |
|
Paget disease |
CK7 | CK20 | CDX2 | ER | MUC1 | GCDFP-15 |
| HER2 | ||||||
|
Sebaceous tumour |
EMA | EpCAM | GCDFP-15 | MLH1 | MSH2 | MSH6 |
| PMS2 | AR | p53 | Ki67 | |||
| Eccrine gland tumour | Tumours luminal (CK7, CEA, EMA) | Myoepithelial (CK5/6, CK14, S100, SOX10) | p40 | Beta-catenin | ||
| BCC/ SCC | EpCAM | CK5/6 | CK14 | p40 | Pan-CK | |
| Autoimmune and Immune-Mediated Diseases (AIM) | FITC-C3 | FITC-fibrinogen | FITC-IgG | FITC-IgA | FITF-IgM | |
| Infectious | HSV-1 | HSV-2 | CMV | Treponema pallidium | VZV | |
|
Other |
CD34 | Factor XIIIa | CD3 | CD31 | CD68 | Ki67 |
| ASMA | Desmin | CD117 | Podoplanin | CD43 | CD63 | |
| CD163 | CD20 | CD4 | CD8 | |||
| The bolded are the most used biomarkers | ||||||
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