CD31, also known as platelet/endothelial cell adhesion molecule 1 (PECAM-1), is a trans-membrane protein expressed on endothelial cells
Intended use
The antibody labels CD31 in normal and neoplastic cells. It is a useful tool for identifying vascular disorder, e.g. angiosarcoma, and evaluating vascularization of tumors when used with a panel of antibodies.
Specifications |
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product code: 8282-C010 |
Clone: RM247 [Rabbit] |
Staining pattern: Membranous staining |
Control tissue: Tonsil, liver, appendix |
Associated panels: Tumor of Unknown Origin - Sarcoma, Dermatopathology |
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Assessment criteria |
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A strong and distinct, predominantly membranous staining of normal endothelial cells and plasma cells in tonsil |
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An at least weak to moderate, distinct membranous staining reaction of activated B- and T-cells, in particular mantle zone B-cells in the tonsil |
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At least weak to moderate staining of hepatic sinusoidal endothelial cells |
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No staining of the epithelial cells in appendix |
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