Estrogen Receptor

Estrogen receptor α is a member of a family of nuclear receptors for small hydrophobic ligands and is
expressed in cells such as normal epithelial cells of mammary glands and normal endometrial and
myometrium cells of the uterus

Intended use

This antibody is useful for assessing estrogen receptor α expression in human breast carcinomas. ER is most often used with other specific breast panel markers. Find more information about breast markers and breast panel antibodies here

Specifications
product code: 8361-C010	Clone: EP1 [Rabbit]
Staining pattern: Nuclear staining	Control tissue: Uterine cervix, Tonsil
Associated panels: Carcinoma - general panel, Breast panel
Assessment criteria
A moderate to strong, distinct nuclear staining of virtually all the columnar epithelial cells, most squamous epithelial and stromal cells (with the exception of endothelial cells and lymphoid cells) in the uterine cervix
An at least weak to moderate nuclear staining reaction in scattered follicular dendritic cells and squamous epithelial cells in the tonsil
No staining of B-cells in mantle zones and within germinal centers in tonsil
Related panels:
Breast panel