Ki67

Ki67 is a proliferation-associated nuclear protein expressed during all active phases of the cell cycle and is absent in resting cells. The antibody labels Ki67 protein in both normal and neoplastic cells.

Intended use

It is a useful tool for assessing proliferative activity of various tumors when used with a panel of antibodies

Specifications
product code: 8473-C010	Clone: GM010 [Mouse]
Staining pattern: Nuclear staining	Control tissue: Tonsil, liver
Associated panels: Breast panel, Gastrointestinal, Dermatopathology
Assessment criteria
A moderate to strong, distinct nuclear staining reaction in 80-90% of the germinal centre B-cells in the dark zone and in the vast majority of the suprabasal squamous epithelial cells of tonsil
A weak to moderate nuclear staining of the majority of B-cells in the light zones of the germinal centres of tonsil
No nuclear staining reaction must be seen in liver