CD20

CD20 is a transmembrane protein expressed on B-cell precursors and mature B-cells, but is lost in plasma cells

Intended use

CD20 is almost always expressed in Bcell lymphomas. The antibody labels CD20 in both normal and neoplastic cells. It is a useful tool for classifying tumor cells of B-lymphocytic lineage when used with a panel of antibodies

Specifications
product code: 8259-C010	Clone: L26 [Mouse monoclonal]
Staining pattern: Membranous staining	Control tissue: Tonsil, appendix
Associated panels: Gastrointestinal, Dermatopathology
Assessment criteria
A strong, predominantly membranous staining of mantle zone B-cells, germinal center B-cells and interfollicular B-cells in tonsil and appendix
No staining of all other cell types