CEA

CEA (Carcinoembryonic Antigen) is a membrane protein expressed on colon and variety of other normal tissues. The antibody labels CEA in normal and neoplastic cells

Intended use

It is a useful tool for classifying adenocarcinomas, especially in the gastrointestinal track including colon and pancreatic adenocarcinomas. It is also a useful tool for classifying secretory meningioma and medullary carcinomas of the thyroid when used with a panel of antibodies

Specifications
product code: 8225-C010	Clone: COL-1 [Mouse]
Staining pattern: Cytoplasmic staining	Control tissue: Tonsil, Appendix, Liver
Associated panels: Carcinoma - general panel, Gastrointestinal
Assessment criteria
A moderate to strong cytoplasmic staining reaction of, at least, scattered squamous epithelial cells/ crypts in tonsil
At least weak to moderate cytoplasmic staining of columnar epithelial cells in appendix with enhancement of glycocalyx
No staining reaction of non-specific cross-reacting antigen in leukocytes and biliary glycoprotein in bile canaliculi of the liver