GATA 3

GATA binding protein 3 (GATA3) is a transcription factor which is involved in regulating development in
multiple tissues.

Intended use

GATA3 is useful for identifying breast carcinoma and urothelial carcinoma when used with a
panel of other antibodies.

Specifications
product code: 8357-C010	Clone: QR018 [Rabbit monoclonal]
Staining pattern: Nuclear staining	Control tissue: Kidney, tonsil
Associated panels: Carcinoma-general panel,  Breast panel
Assessment criteria
An at least moderate, distinct nuclear staining reaction of virtually all epithelial cells in collecting ducts and podocytes in renal glomeruli
An at least moderate nuclear staining reaction of the majority of T helper cells (particularly Th2 cells) in the T-zones in the tonsil and dispersed T-cells in all tissues
No staining of B-cells should be seen