Vimentin

Vimentin is an intermediate filament protein that forms part of the cytoskeleton, and is expressed ubiquitously in mesenchymal cells such as fibroblasts, smooth muscle cells, and endothelium.

Intended use

Vimentin is useful for classifying neoplastic tissues of mesenchymal origin such as soft tissue tumors when used with a panel of other antibodies.

Specifications
product code: 8336-C010	Clone: V9 [Mouse]
Staining pattern: Cytoplasmic staining	Control tissue: Appendix, liver
Associated panels: Tumor of Unknown Origin
Assessment criteria
A strong and distinct cytoplasmic staining reaction must be shown in virtually all lymphocytes (including intra-epithelial T-Cells), endothelial cells, stromal cells and macrophages in appendix
		An at least weak to moderate and distinct cytoplasmic staining reaction must be seen in virtually all Kupffer cells in the liver
An at least weak staining reaction must be displayed in endothelial cells of the sinusoids in the liver
No staining reaction of epithelial cells in the appendix and of hepatocytes in the liver
Panels:
Tumor of unknown Origin