Progesterone Receptor (PR)

Progesterone Receptor is a ligand-activated transcription factor and a member of the steroid receptor family. PR is predominantly expressed in female sex steroid responsive tissues such as the mammary gland, uterus, and ovary but is also expressed in other tissues such as endocrine cells of pancreatic islets.

Intended use

Anti-PR antibody is a useful tool for assessing PR expression in human breast carcinomas

Specifications
product code: 8360-C010	Clone: Y85 [Rabbit]
Staining pattern: Nuclear staining	Control tissue: Uterine cervix, Tonsil
Associated panels: Breast panel
Assessment criteria
A moderate to strong, distinct nuclear staining reaction of virtually all stromal cells and columnar epitheliar cells in the uterine cervix.
An at least weak but distinct nuclear staining reaction in most basal squamous epithelial cells in the uterine cervix
No nuclear staining reaction of cells in the tonsil