Neuron Specific Enolase (NSE)

Neuron-specific enolase (NSE) is a gamma subunit homodimer and is the dominant form of the enolase
isoenzymes found in neuronal and neuroendocrine cells.

Intended use

Anti-NSE antibody is a useful tool for the identification of neuronal and neuroendocrine derived tumors such as neuroblastomas, retinoblastomas, desmoplastic malignant melanoma, and small-cell lung cancer, when used with a panel of antibodies

Specifications
product code: 8447-C010	Clone: EP319 [Rabbit]
Staining pattern: Nuclear and/ or cytoplasmic staining	Control tissue: Appendix, colon, pancreas
Assessment criteria
Cytoplasmic and nuclear staining of neurons in brain, ganglion cells in gastrointestinal tract, myelinated and unmyelinated nerve fibers, as well as tumors derived from or containing neurons, ganglion cells, and peripheral nerves
Moderate to strong cytoplasmic and nuclear staining of adrenal cortex and islet cells of pancreas
Cytoplasmic staining of smooth muscle cells, and some renal epithelium and T-cells