Myeloperoxidase

Myeloperoxidase (MPO) is a peroxidase enzyme involved in antimicrobial activity. MPO is synthesized and expressed in precursor and mature granulocytes, including neutrophils and eosinophils, and is variably
expressed in monocytes/macrophages.

Intended use

Anti-MPO antibody is useful for detecting myeloid cell populations in bone marrow and other tissue sites, and for differentiating between myeloid and lymphoid neoplasms, when used with a panel of other antibodies.

Specifications
product code: 8407-C010	Clone: EP151 [Rabbit]
Staining pattern: Cytoplasmic staining	Control tissue: Liver, tonsil
Assessment criteria
A strong granular cytoplasmic staining of the neutrophils and Kupffer cells in liver
A moderate to strong, granular cytoplasmic staining of neutrophils and eosinophils in the interfollicular zones and of macrophage in the germinal center in tonsil
A negative or weak staining of hepatocytes in liver