Melanoma Pan

PMEL17 (a melanosome marker), MART-1 (Melan-A), and tyrosinase are proteins expressed in normal
melanocytes, and are often detected in melanomas

Intended use

Through detection of these proteins via immunohistochemistry, anti-Melanoma Pan antibody cocktail is a useful tool for identifying melanomas, when used with a panel of antibodies.

Specifications
product code: 8371-C010	Clone:  HMB45/EP43/T311 [Cocktail]
Staining pattern: Cytoplasmic staining	Control tissue: Blue nevus, skin, kidney
Associated panels: Dermatopathology
(Assessment criteria)/ examples
Strong, distinct cytoplasmic staining reaction of virtually all melanocytes in skin A weak to moderate reaction in the melanocytic dendrites in most melanocytes in skin
An at least weak to moderate cytoplasmic staining reaction of the majority of neoplastic cells of blue nevus or angiomyolipoma
No staining in the epithelial cells of tubulus in kidney
* Scattered epithelial cells may show a granular staining reaction caused by lipofuscin