Gastrin is a peptide hormone that stimulates production gastric acid by the parietal cells of the stomach, and also aids in gastric motility. Gastrin is produced by G-cells in the pyloric antrum of stomach, and evidence suggests an important role for gastrin and its target cell, the enterochromaffin-like cell, in gastric carcinogenesis.
Intended use
Staining with the Tissue-Tek Genie anti-Gastrin Rabbit Polyclonal Antibody may be useful in the identification of gastric neuroendocrine tumors, when used with a panel of antibodies
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Specifications |
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product code: 8314-C010 |
Clone: Poly [Rabbit] |
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Staining pattern: Cytoplasmic staining |
Control tissue: Stomach |
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Associated panels: Gastrointestinal |
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Assessment criteria |
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A moderate to strong cytoplasmic staining of G-cells in stomach |
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No staining of epithelial cells in stomach |
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*a slightly diffuse staining from G-cells may be observed |
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