Gastrin

Gastrin is a peptide hormone that stimulates production gastric acid by the parietal cells of the stomach, and also aids in gastric motility. Gastrin is produced by G-cells in the pyloric antrum of stomach, and evidence suggests an important role for gastrin and its target cell, the enterochromaffin-like cell, in gastric carcinogenesis.

Intended use

Staining with the Tissue-Tek Genie anti-Gastrin Rabbit Polyclonal Antibody may be useful in the identification of gastric neuroendocrine tumors, when used with a panel of antibodies

Specifications
product code: 8314-C010	Clone: Poly [Rabbit]
Staining pattern: Cytoplasmic staining	Control tissue: Stomach
Associated panels: Gastrointestinal
Assessment criteria
A moderate to strong cytoplasmic staining of G-cells in stomach
No staining of epithelial cells in stomach
*a slightly diffuse staining from G-cells may be observed