CD57

CD57 is a marker of hemopoietic and neuroectodermal derived cells. CD57 is expressed on subtypes of T-cells, natural killer (NK) cells, and other peripheral blood mononuclear cells. CD57 is also present in glia
cells and a variety of other neural and epithelial cells

Intended use

CD57 is seen in various neural tumors. In addition, CD57 is expressed in prostate tissue, prostate adenocarcinoma, papillary thyroid carcinomas, thymomas. CD57 is useful in classifying subtypes of Hodgkin’s lymphoma and T-cell large granular lymphocyte disorders. The anti-CD57 antibody is a useful aid for classifying lymphoid neoplasms when used in a panel with other antibodies.

Specifications
product code: 8338-C010	Clone: NK1 [Mouse]
Staining pattern: Membranous staining	Control tissue:  Tonsil, liver
Assessment criteria
A strong staining reaction in NK cells in germinal centre in the tonsil
A weak staining reaction in scattered T-cells in liver and tonsil