CD138

CD138, also known as Syndecan-1, is a membrane protein which is involved in regulating cell morphology and adhesion. CD138 is predominantly expressed on mature plasma cells and early pre B-cells. Various types of epithelial cells are CD138 positive, whereas mature mesenchymal and neural tissues are negativ

Intended use

CD138 is expressed in plasma cell malignancies. Anti-CD138 antibody is a useful tool for identifying plasma cells and plasma cell differentiation within hematolymphoid tissues when used with a panel of antibodies.

Specifications
product code: 8241-C010	Clone: B-A38 [Mouse]
Staining pattern: Membranous staining	Control tissue: Tonsil
Assessment criteria
A strong predominantly membranous staining reaction must be shown in plasma cells and squamous epithelial cells in tons
A weak to moderate and distinct membranous staining reaction must be shown in late stage activated germinal center B-cells in tonsil
No staining reaction is seen in mantle zone B-cells