Perforin

Perforin is a key molecule for cytotoxicity mediated by T-cells and natural killer cells. It is expressed in the
cytoplasmic granule of cytotoxic T-lymphocytes (CTLs) and natural killer (NK) cells, and is a specific marker of functionally active CTLs and NK cells.

Intended use

Anti-perforin antibody is useful for identifying functional active CTLs and NK cells in tissues and for aid in differentiating peripheral T-cell lymphomas and NK cell lymphoma from other lymphomas when used in a panel with other antibodies.

Specifications
product code: 8236-C010	Clone: 5B10 [Mouse]
Staining pattern: Cytoplasmic staining	Control tissue: Tonsil
Assessment criteria
A weak to moderate staining reaction of the majority of T-cells in tonsil