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Perforin is a key molecule for cytotoxicity mediated by T-cells and natural killer cells. It is expressed in the
cytoplasmic granule of cytotoxic T-lymphocytes (CTLs) and natural killer (NK) cells, and is a specific marker of functionally active CTLs and NK cells.
Intended use
Anti-perforin antibody is useful for identifying functional active CTLs and NK cells in tissues and for aid in differentiating peripheral T-cell lymphomas and NK cell lymphoma from other lymphomas when used in a panel with other antibodies.
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Specifications |
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product code: 8236-C010 |
Clone: 5B10 [Mouse] |
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Staining pattern: Cytoplasmic staining |
Control tissue: Tonsil |
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Assessment criteria |
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A weak to moderate staining reaction of the majority of T-cells in tonsil |
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