Hepatocyte

Hepatocyte Specific Antigen, also known as Hepatocyte Paraffin 1 (Hep Par 1), is expressed in normal and neoplastic hepatocytes

Intended use

Hep Par 1 is a highly specific marker for hepatocyte carcinoma (HCC), although several non-hepatic  tumors occasionally can show some Hep Par 1 positivity. The anti-Hep Par 1 antibody is useful in  differentiating HCC from the metastatic lesions to liver, and hepatoblastoma from other small round cell tumors when used with a panel of other antibodies.

Specifications
product code: 8374-C010	Clone: OCH1E5 [Mouse]
Staining pattern: Cytoplasmic staining	Control tissue: Liver, Tonsil
Associated panels: Carcinoma - general panel, Gastrointestinal
Assessment criteria
moderate to strong granular cytoplasmic staining reaction of virtually all the hepatocytes in the liver
No staining reaction of the bile ductal epithelial cells in the liver
No staining reaction in the tonsil