CD79a

CD79a is a membrane protein expressed on B-cells from precursors through plasma cells. CD79a is also found to be expressed in 10% of T-lympho-blastic leukemia/lymphoma. The antibody labels CD79a in normal and neoplastic cells

Intended use

CD79a is a useful tool for classifying B-cell neoplasms and Hodgkin’s disease when used with a panel of antibodies.

Specifications
product code: 8278-C010	Clone: GR019 [Rabbit]
Staining pattern: Membranous and/or cytoplasmic staining	Control tissue: Tonsil, appendix
Associated panels: Gastrointestinal
Assessment criteria
A strong, predominantly membranous staining of mantle zone B-cells in tonsil
A strong, predominantly cytoplasmic staining of plasma cells and immunoblasts in germinal centers in tonsil
An at least moderate membranous staining of germinal center B-cells in secondary follicles in tonsil
No staining of epithelial cells in appendix. NB. Plasma cells in lamina propria show a strong cytoplasmic staining reaction