Robert Heijmen
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Articles
Recent activity by Robert Heijmen-
PD-1
Programmed-death ligand 1 (PD-1) is a transmembrane protein and the receptor for PD-L1 and PD-L2 ligands. PD-1 is a coinhibitory receptor of lymphocytes and other immune system cel...
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PAX8
PAX8 is a transcription factor that is important for organogenesis and development of the thyroid, urogenital tract, and placenta. PAX8 is expressed in epithelial cells of the urog...
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PAX5
PAX5, also designated B-cell specific activator protein (BSAP), is a transcription factor of the paired-box (PAX) containing family. PAX5 is important in control of B-cell commitme...
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p120
p120 catenin binds E-Cadherin at a juxta-membrane site while alpha-catenin and beta-catenin bind to theintracellular domain of E-Cadherin. A deficiency of E-Cadherin results in the...
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OCT.2
OCT.2 is a transcription factor that binds to the immunoglobulin gene and interacts with BOB.1. It is essential for expression of B-cell specific genes. OCT.2 is expressed in matu...
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NKX3.1
NKX3.1 is an androgen-regulated tumor suppressor gene. NKX3.1 protein down regulate growth of epithelial cells in prostate tissue and plays a critical role in suppressing prostate ...
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Neuron Specific Enolase (NSE)
Neuron-specific enolase (NSE) is a gamma subunit homodimer and is the dominant form of the enolaseisoenzymes found in neuronal and neuroendocrine cells. Intended use Anti-NSE ant...
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Neurofilament
Neurofilaments are cytoskeletal proteins normally found in neurons and axonal processes. They are often found in tumors of neural, neuroendocrine, and endocrine origin, including...
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Napsin A
Napsin A is a protease that is predominantly expressed in the lung and kidney. Napsin A is expressed inalveolar type II pneumocytes in lung and proximal tubules in kidney. Intended...
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Myosin Smooth Muscle (SMMS-1)
Myosin is one of the major contractile proteins in muscle and non-muscle cells. It involves in conversion of chemical energy into mechanical work. A Myosin molecule consists of two...