Robert Heijmen
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Articles
Recent activity by Robert Heijmen-
DUO p40 / Napsin A
The ΔNp63 isoform, also known as p40, is the predominant isoform of p63 that is truncated, or lacking the N-terminal domain. p40 is a nuclear protein and a transcription factor. It...
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p40/ Myosin
The ΔNp63 isoform, also known as p40, is the truncated or lacking the N-terminal domain and predominant isoform of p63. p40 is a nuclear protein and a transcription factor. It is con...
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p40
The ΔNp63 isoform, also known as p40, is the truncated or lacking the N-terminal domain and predominant isoform of p63. p40 is a nuclear protein and a transcription factor. It is con...
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PD-L1
The programmed-death ligand 1 (PD-L1, also known as CD274) is a transmembrane protein constitutionally expressed on a variety of cell types. When PD-L1 binds the checkpoint molecu...
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SMAD4
The SMAD family 4 (SMAD4) or deleted in pancreatic cancer 4 (DPC4) is a tumor suppressor gene that isinactivated in a sub-set of pancreatic adenocarcinomas. Somatic mutations of SMAD...
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DUO Melan A/ Ki67
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CK5/6 / TTF1
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PIN cocktail
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Breast panel
Differential diagnosis Most commonly used biomarkers Breast carcinoma GATA3 Mammaglobin GCDFP-15 ER CK5/6 CK14 CK8/18 CK7 CK20 DCIS vs. infiltrating ductal...
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Carcinoma - general panel
In case of known/ suspected carcinoma, but unknown origin, this table can be used to identify the tumor origin: CK7 CK20 Origin positive negative + - Lung TTF-1, Napsin A PAX8, GATA3 ...